ICU Researchers Information System - MIZOGUCHI, Tsuyoshi |

（Last updated : 2019-12-16 15:47:29）

MIZOGUCHI, Tsuyoshi

Professor

Division of Arts and Sciences, College of Liberal Arts, International Christian University

■ Academic Background

1.	1991/04～1995/03	Graduate School, Division of Bioresearch, University of Tsukuba, Completed, PhD
2.	1987/04～1991/03	University of Tsukuba, Graduated

■ #Professional Background

1.	2017/04～2018/03	Cabinet Office of Government of Japan
2.	2016/04～	Director of Center for Research Planning and Support, Center for Research Planning and Support, International Christian University
3.	2015/04～2018/03	Chair of Department of Natural Sciences, Department of Natural Sciences, International Christian University
4.	2014/04～2015/03	Chair of Department of Life Science, Department of Life Science, International Christian University
5.	2012/04～	Professor, International Christian University
6.	2012/04～2014/03	DNA Lab Safety Officer, International Christian University
7.	2010/04～2012/03	Head of Basic Technology Research Division, Plant Transgenic Design Initiative, University of Tsukuba
8.	2008/04～2012/03	Deputy Director, Gene Research center, University of Tsukuba
9.	2007/04～2012/03	Associate Professor, Gene Research Center, University of Tsukuba
10.	2006/06～2007/03	Assistant Professor, Gene Research Center, University of Tsukuba
11.	2002/03～2006/06	Lecturer, Gene Research Center, University of Tsukuba
12.	1999/12～2001/12	HFSP Long-term fellow, John Innes Centre
13.	1997/04～2002/02	Research Associate, RIKEN
14.	1995/04～1997/03	Post-doctoral fellow, RIKEN
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■ #Present Specialized Fields

Environmental agriculture(including landscape science), Plant molecular biology/Plant physiology, Molecular biology

■ #Main Course Titles

Plant Physiology, Basic Concepts in Plant Physiology , Laboratory in Plant Physiology

■ #Books and Articles

1.	Article	Ubiquitin carboxyl-terminal hydrolases are required for period maintenance of the circadian clock at high temperature in Arabidopsis. Scientific Reports (Collaboration) 2019
2.	Article	Differential effects of light-to-dark transitions on phase setting in circadian expression among clock-controlled genes in Pharbitis nil. Plant Signal & Behavior (Collaboration) 2018
3.	Article	Evaluation of internal control genes for quantitative realtime PCR analyses for studying fruit development of dwarf tomato cultivar 'Micro-Tom'. Plant Biotechnology (Collaboration) 2018
4.	Article	A loss-of-function mutateon in the DWARF4/PETANKO5 gene enhances the late-flowering and semi-dwarf phenolypes of the Arabidopsis clock mutant lhy-12;cca1-101 under continuous light without affecting FLC expression. Plant Biotechnology 33,pp.315-321 (Collaboration) 2016
5.	Article	Density effects on late flowering mutants of Arabidopsis thaliana under continuous light. Plant Biotechnology 33,pp.323-331 (Collaboration) 2016
6.	Article	Density effects on semi-dwarf and early flowering mutants of Arabidopsis thaliana under continuous light. Plant Biotechnology 33,pp.333-339 (Collaboration) 2016
7.	Article	The FT-like gene PehFT in petunia responds to photoperiod and light quality but is not the main gene promoting light quality-associated flowering. Plant Biotechnology 33,pp.297-307 (Collaboration) 2016
8.	Article	CO-EXPRESSED WITH CLOCK GENES LHY AND CCA1 1 (CEC1) is regulated by LHY and CCA1 and plays a key role in phase setting of GI in Arabidopsis thaliana. Plant Biotechnology 31,pp.35-41 (Collaboration) 2014
9.	Article	EMS mutagenesis and characterization of Brassica rapa mutants. Plant Biotechnology 31,pp.185-190 (Collaboration) 2014
10.	Article	Increase in vascular pattern complexity caused by mutations in LHY and CCA1 in Arabidopsis thaliana under continuous light. 31,pp.43-47 (Collaboration) 2014
11.	Article	Comparative analysis of common genes involved in early fruit development in tomato and grape. 30,pp.295-300 (Collaboration) 2013
12.	Article	Late flowering phenotype under ultra-short photoperiod (USP) in Arabidopsis thaliana. 31,pp.29-34 (Collaboration) 2013
13.	Article	The unique function of the Arabidopsis circadian clock gene PRR5 in the regulation of shade avoidance response. Plant Signal Behav 8,pp.e23534 (Collaboration) 2013
14.	Article	Abiotic stress and role of salicylic acid in plants. Abiotic stress responses in plants. pp.235-251 (Collaboration) 2012
15.	Article	A trial of production of the plant-derived high-value protein in a plant factory: Photosynthetic photon fluxes affect the accumulation of recombinant miraculin in transgenic tomato fruits. Plant Signaling & Behavior 6,pp.1172-1179 (Collaboration) 2011
16.	Article	Calmodulin-dependent activation of MAP kinase for ROS homeostasis in Arabidopsis. Molecular Cell 41,pp.649-660 (Collaboration) 2011
17.	Article	Double loss-of-function mutation in EARLY FLOWERING 3 and CRYPTOCHROME 2 genes delays flowering under continuous light but accelerates it under long-days and short-days: An important role of Arabidopsis CRY2 to accelerate flowering time in continuous light. Journal of Experimental Botany 62,pp.2731-2744 (Collaboration) 2011
18.	Article	Suppression of late-flowering and semi-dwarf phenotypes in the Arabidopsis clock mutant lhy-12;cca1-101 by phyB under continuous light. Plant Signaling & Behavior 6,pp.1162-1171 (Collaboration) 2011
19.	Article	TOMATOMA: A novel tomato mutant database distributing Micro-Tom mutant collections. Plant and Cell Physiology 52,pp.283-296 (Collaboration) 2011
20.	Article	Tomato TILLING technology: development of a reverse genetics tool for the efficient isolation of mutants from Micro-Tom mutant libraries. Plant Cell Physiol 52,pp.1994-2005 (Collaboration) 2011
21.	Article	Isolation and characterization of suppressors of the early flowering 3 in Arabidopsis thaliana. Plant Biotechnology 27,pp.463-468 (Collaboration) 2010
22.	Article	Molecular breeding of tomato lines for mass production of miraculin in a plant factory. Journal of Agricultural and Food Chemistry 58,pp.9505-9510 (Collaboration) 2010
23.	Article	Photoperiod pathway regulates expression of MAF5 and FLC that encode MADS-box transcription factors of the FLC family in Arabidopsis. 27,pp.447-454 (Collaboration) 2010
24.	Article	Possible involvement of FLC in natural variation of activity to enhance the late flowering phenotype of the clock mutant lhy cca1 under continuous light. Plant Biotechnology 27,pp.455-461 (Collaboration) 2010
25.	Article	Isolation of suppressors of late flowering and abnormal flower shape phenotypes caused by overexpression of the SHORT VEGETATIVE PHASE gene in Arabidopsis thaliana. Plant Biotechnology 26,pp.217-224 (Collaboration) 2009
26.	Article	Possible role of EARLY FLOWERING 3 (ELF3) in the clock-dependent floral regulation by SHORT VEGETATIVE PHASE (SVP) in Arabidopsis. New Phytologist 182,pp.838-850 (Collaboration) 2009
27.	Article	Circadian clock proteins LHY and CCA1 regulate SVP protein accumulation to control flowering in Arabidopsis. Plant Cell 20,pp.2960-2971 (Collaboration) 2008
28.	Article	Roles of Arabidopsis PSEUDO-RESPONSE REGULATOR (PRR) genes in the opposite controls of flowering time and organ elongation under long-day and continuous light conditions. Plant Biotechnology 25,pp.165-172 (Collaboration) 2008
29.	Article	Arabidopsis clock-associated pseudo-response regulators PRR9, PRR7 and PRR5 coordinately and positively regulate flowering time through the canonical CONSTANS-dependent photoperiodic pathway. Plant Cell Physiol. 48,pp.822-832 (Collaboration) 2007
30.	Article	Ethylmethanesulfonate (EMS)-mutagenesis of Solanum lycopersicum cv. Micro-Tom for large scale screening of mutants. Plant Biotechnology 24,pp.33-38 (Collaboration) 2007
31.	Article	Genetic linkages between circadian clock-associated components and phytochrome-dependent red light signal transduction in Arabidopsis thaliana. Plant Cell Physiol. 48,pp.971-983 (Collaboration) 2007
32.	Article	Genetic linkages of the circadian clock-associated genes, TOC1, CCA1 and LHY, in the photoperiodic control of flowering time in Arabidopsis thaliana. 48,pp.925-937 (Collaboration) 2007
33.	Article	Isolation of novel gain- and loss-of-function alleles of the circadian clock gene LATE ELONGATED HYPOCOTYL (LHY) in Arabidopsis. Plant Biotechnology 24,pp.457-465 (Collaboration) 2007
34.	Article	Natural variation of polyglutamine repeats of a circadian clock gene ELF3 in Arabidopsis. Plant Biotechnology 24,pp.237-240 (Collaboration) 2007
35.	Article	The mitogen-activated protein kinase cascade MKK3-MPK6 is an important part of the jasmonate signal transduction pathway in Arabidopsis. Plant Cell 19,pp.805-818 (Collaboration) 2007
36.	Article	Antagonistic interaction between MAP kinase and protein phosphatase 2C in stress recovery. Plant Science 171,pp.596-606 (Collaboration) 2006
37.	Article	Circadian clock components in Arabidopsis III. Roles of the circadian clock components LHY/CCA1/GI in regulating the floral integrator genes LFY/SOC1/FT to control flowering time and shoot architecture. Plant Biotechnology 22,pp.327-331 (Collaboration) 2005
38.	Article	Circadian clock components in Arabidopsis II. The circadian clock components LHY/CCA1 regulate the floral integrator gene SOC1 in both GI-dependent and –independent pathways. Plant Biotechnology 22,pp.327-331 (Collaboration) 2005
39.	Article	Circadian clock components in Arabidopsis I. The terminal flower 1 enhances the early flowering phenotype of a circadian clock mutant, lhy cca1. Plant Biotechnology 22,pp.311-317 (Collaboration) 2005
40.	Article	Distinct roles of GIGANTEA in promoting flowering and regulating circadian rhythms in Arabidopsis. Plant Cell 17,pp.2255-2270 (Collaboration) 2005
41.	Article	Isolation of Arabidopsis mutants that have altered sensitivity to staurosporine and ABA. Plant Biotechnology 22,pp.303-310 (Collaboration) 2005
42.	Article	Antisense suppression of the Arabidopsis PIF3 gene does not affect circadian rhythms but causes early flowering and increases FT expression. FEBS Letters 557,pp.259-264 (Collaboration) 2004
43.	Article	Possible involvement of leaf gibberellins in the clock-controlled expression of XSP30, a gene encoding a xylem sap lectin, in cucumber roots. Plant Physiology 133,pp.1-12 (Collaboration) 2003
44.	Article	LHY and CCA1 are partially redundant genes required to maintain circadian rhythms in Arabidopsis. Developmental Cell 2,pp.629-641 (Collaboration) 2002
45.	Article	Salinity and genotoxic stress responses converge on Arabidopsis MAP kinase phosphatase 1. EMBO Journal 21,pp.6483-6493 (Collaboration) 2002
46.	Other	Environmental responses of plants: Biological interactions in the homogenyous population or community (mixed populations). Plant Biotechnology 33,pp.211-212 (Collaboration) 2016
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■ #Academic Conference Presentation

1.	2017/11/26	Inversion of photoperiodic response by mutations of circadian clock genes in Arabidopsis thaliana (Tunisia-Japan Symposium on Science, Society and Technology (TJASSST 2017))
2.	2016/11/25	Density effects on late and early flowering mutants of Arabidopsis thaliana under continuous light (The 13th Japan Solanaceae Consortium (JSOL 2016))
3.	2016/11/25	Effect of night break on flowering time and FT expression in elf3;gi, an SDP-type mutant of Arabidopsis thaliana (The 13th Japan Solanaceae Consortium (JSOL 2016))
4.	2016/11/25	Effect of night break on flowering time and FT expression in elf3;gi, an SDP-type mutant of Arabidopsis thaliana (The 13th Japan Solanaceae Consortium (JSOL 2016))
5.	2016/11/25	Identification of PH-domain-containing RAB5 effectors (The 13th Japan Solanaceae Consortium (JSOL 2016))
6.	2016/11/25	Inversion of photoperiodic response by double loss-of-function mutations in EARLY FLOWERING 3 and GIGANTEA in Arabidopsis thaliana (The 13th Japan Solanaceae Consortium (JSOL 2016))
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■ #Teaching Experience

1.	Foundation of Biology（International Christian University）
2.	Laboratory in Foundation of Biology（International Christian University）
3.	学際科学総合演習（国際基督教大学）
4.	Research II（International Christian University）
5.	Research III（International Christian University）
6.	Plant-microbe Interactions（International Christian University）
7.	Plant Physiology（International Christian University）
8.	植物生理学実習（国際基督教大学）
9.	Basic Concepts in Plant Physiology（International Christian University）
10.	Plant Development（International Christian University）
11.	生化学実習（国際基督教大学）
12.	Advanced Studies in Biology I（International Christian University）
13.	Advanced Studies in Biology II（International Christian University）
14.	Advanced Seminar in Biology II（International Christian University）
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■ #Research Topics, Funded Research, and Grants-in-Aid for Scientific Research

2017/04～2020/03

Understanding of a mechanism underlying a control of flowering time by photoperiod (Key Word : )

■ #Grants-in-aid for Scientific Research Researcher Number

70281623